Ultrastructural changes in internal anal sphincter in neurogenic faecal incontinence.

Ultrastructural changes in internal anal sphincter in neurogenic faecal incontinence.

The ultrastructural features of the internal anal sphincter (IAS) muscle were studied in biopsies from five patients with neurogenic anorectal incontinence and six control subjects undergoing anorectal excision for cancer, or for inflammatory bowel disease. In the patients with idiopathic neurogenic anorectal incontinence the internal anal sphincter showed loss of smooth muscle cells, disruptio...

Progressive systemic sclerosis of the internal anal sphincter leading to passive faecal incontinence.

Two female patients aged 62 and 44 years with progressive systemic sclerosis and passive faecal incontinence are described. Both had the typical gut motility disorders of dysphagia, heartburn, and constipation. Anorectal physiology tests showed a low resting pressure in both and an absent rectoanal inhibitory reflex in one. In both patients anal endosonography showed a thin internal anal sphinc...

Anal endosonography in faecal incontinence.

The internal and sphincter--new insights into faecal incontinence.

Ultrastructural analysis of changes in neurons of the mouse internal anal sphincter during ageing

N. (2013). Ultrastructural analysis of changes in neurons of the mouse internal anal sphincter during ageing. Copyright and Moral Rights for the articles on this site are retained by the individual authors and/or other copyright owners. For more information on Open Research Online's data policy on reuse of materials please consult the policies page. Aging is the main risk factor for most chroni...